Areas of Expertise
Cell and Molecular Biology and Biochemistry
Courses currently taught: Molecular Biology Techniques, Molecular Biology and Biochemistry, Molecular Biology and Biochemistry Lab
B.A. (Biochemistry) Wilkes University (1994)
Ph.D. (Biochemistry Program) The Ohio State University (1998)
Post-doctoral training – University of Florida, Whitney Laboratory
The mechanisms through which neural cell metabolism is supported is my current focus of study. Specifically, I investigate members of the Basigin subset of the immunoglobulin superfamily (IgSF) and the roles they play in the metabolic aspects of sensory systems. Members of this subset of the IgSF often interact with monocarboxylate transporters (MCTs), that are known to move pyruvate, lactate, and ketone bodies across a plasma membrane via facilitated diffusion. We use cell and molecular biology and biochemistry techniques to answer questions related to the interactions between Basigin IgSF family members and MCTs, both in cis (on the same cell) and in trans (across two different cells) to ultimately understand how those interactions support the metabolic needs of neural systems.
• UNF Outstanding Faculty Service Award, nominee, April 2015
• UNF Mentor of the Year Award, nominee, April 2015
• UNF Susan B. Anthony Award, nominee, November 2014
• UNF Outstanding Faculty Service Award, nominee, April 2014
• UNF Mentor of the Year Award, nominee, April 2013
• UNF Mentor of the Year Award, April 2012
• UNF Outstanding Undergraduate Teaching Award, April 2012
• UNF Outstanding Graduate Teaching Award finalist, February 2012
• UNF Mentor of the Year Award, 1st runner-up, April 2011
• UNF Mentor of the Year Award, nominee, April 2010
• UNF Outstanding Undergraduate Teaching Award, April 2009
• UNF Outstanding Undergraduate Teaching Award finalist, February 2008
• American Society for Biochemistry and Molecular Biology, 2014 – present
• American Society for Cell Biology, 1999 – present
Grants and Contracts Awarded
• UNF Transformational Learning Opportunity Grant, 2015 – 2016, $13,600
• UNF Summer Proposal Development Grant, 2015, $10,000
• UNF Transformational Learning Opportunity Grant, 2013 – 2014, $13,000
• UNF Transformational Learning Opportunity Grant, 2012 – 2013, $13,900
• UNF Summer Scholarship Grant, 2012, $7500
• UNF Summer Proposal Development Grant, 2011, $7500
• UNF COAS Dean’s Leadership Council Faculty Fellowship, 2011, $4000
• UNF Summer Teaching Grant, 2010, $7,500
• UNF Transformational Learning Opportunity Grant, 2009 – 2010, $20,000
• UNF Summer Scholarship Grant, 2009, $7,500
• UNF Summer Proposal Development Grant, 2008, $7,500
• UNF Summer Scholarship Grant, 2007, $7,500
• UNF Summer Scholarship Grant, 2006, $5,000
Publications & Presentations
* Denotes undergraduate or graduate student author
Pablo, K.A.V.* and Ochrietor, J.D. (2013) Deletion of the Basigin gene results in reduced
mitochondria in the neural retina. Biochemical and Biophysical Research Communications 438, 546-550. DOI 10.1016/j.bbrc.2013.07.092
Olsen, K.*, Ritson-Williams, R., Ochrietor, J.D., Paul, V.J., and Ross, C. (2013) Detecting
hyperthermal stress in larvae of the hermatypic coral Porites astreoides: The suitability of using biomarkers of oxidative stress versus heat shock protein expression. Marine Biology, in press, DOI 10.1007/s00227-013-2255-z
Ochrietor, J.D., Moroz, T. P., and Linser, P.J. (2010) The 2M6 antigen is a Müller cell-specific
intracellular membrane-associated protein of the sarcolemmal membrane-associated protein family and is also TopAP. Molecular Vision 16, 961-969.
Howard, J.*, Finch, N. A.*, and Ochrietor, J.D. (2010) Characterization of monocarboxylate
transporter 1 (MCT1) binding affinity for Basigin gene products and L1cam. Cellular and Molecular Neurobiology, 30, 671-674. DOI 10.1007/s10571-010-9503-2.
Finch, N. A.*, Linser, P. J., and Ochrietor, J. D. (2009) Hydrophobic interactions stabilize the
Basigin-MCT1 complex. Protein Journal 28, 362-368. DOI 10.1007/ s10930-009-9202-3.
Ochrietor, J. D., Clamp, M. F.*, Moroz, T. P., Grubb, J. H., Shah, G. N., Waheed, A., Sly, W.
S., and Linser, P. J. (2005) Carbonic anhydrase-XIV identified as the membrane
CA in mouse retina: Strong expression in Müller cells and the RPE. Exp. Eye Res 81, 492-500.
Ochrietor, J. D. and Linser, P. J. (2004) 5A11/Basigin gene products are necessary for proper
maturation and function of the retina. Dev Neurosci, 26, 380-387.
Clamp, M. C.*, Ochrietor, J. D., Moroz, T. P., and Linser, P. J. (2004) Developmental
expression of 5A11/Basigin family members in the mouse retina. Exp Eye Res 78,
Ochrietor, J. D., Moroz, T. P., van Ekeris, L., Clamp, M. F.*, Jefferson, S. C.*, deCarvalho, A.
C., Fadool, J. M., Wistow, G., Muramatsu, T., and Linser, P. J. (2003) Retina-
specific expression of 5A11/Basigin-2, a member of the immunoglobulin gene
superfamily. Invest Ophthalmol Vis Sci 44, 4086-4096.
Philp, N. J., Ochrietor, J. D., Rudoy, C., Muramatsu, T., and Linser, P. J. (2003) Loss of MCT1,
MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina
of the 5A11/basigin-null mouse. Invest Ophthalmol Vis Sci 44, 1305-1311.
Corena, M. D. P., Seron, T. J.*, Lehman, H. K., Tu, T., Ochrietor, J. D., Kohn, A.B., and
Linser, P. J. (2002) Carbonic anhydrase in the midgut of Aedes aegypti larvae:
Cloning, localization, and inhibition. J Exp Biol 205, 591-602.
Ochrietor, J. D., Moroz, T. P., Clamp, M. F.*, Timmers, A. M., Muramatsu, T., and Linser, P. J.
(2002) Inactivation of the Basigin gene impairs normal retinal development and
maturation. Vision Res 42, 447-453.
Ochrietor, J. D., Moroz, T. M., Kadomatsu, K., Muramatsu, T., and Linser, P. J. (2001) Retinal
degeneration following failed photoreceptor maturation in 5A11/basigin null
mice. Exp Eye Res 72, 467-477.
Ochrietor, J. D., Harrison, K.*, Zahedi, K., and Mortensen, R. F. (2000) Role of STAT3 and
C/EBP in cytokine-dependent expression of the mouse serum amyloid P
component (SAP) and mouse C-reactive protein (CRP) genes. Cytokine 12, 888-