UNIVERSITY OF NORTH FLORIDA
COLLEGE OF HEALTH
DEPARTMENT OF HEALTH SCIENCE

COURSE TITLE; NUTRITION AND METABOLISM II

COURSE NUMBER; HUN. 6331

PREREQUISITES; HSC. 4572, BCH 3023, 

OR INSTRUCTORS AGREEMENT

NUMBER OF CREDITS: 3

FACULTY;SIMIN B. VAGHEFI PhD., CNS., LN

Revised Spring 2002

TEXTBOOK REQUIRED: HUNT AND GROFF; ADVANCED NUTRITION AND HUMAN METABOLISM  WEST 2000

REQUIRED REFERENCES:

1, Nutrition Reviews (Journal)

2. Nutrition Today (Journal)

3. American Journal of Clinical Nutrition (Journal)

4. The Journal of Nutrition (Journal)

5. Metabolism (Journal)

6. Annual Reviewsof Nutrition 

Students are required to keep up-to-date with the above journals and other relevant journals and be prepared to present at least one summery articles of their readings from the above journals at each session.

COURSE DESCRIPTION:

Biochemical function and metabolism of micronutrients, function and nature of the vitamins, biosynthesis and metabolism of enzymes, their regulatory role as coenzyme and essentialness and bioavailability of minerals, and other recently described essential nutrients are covered. Biochemical basis for deficiency and toxicity of micronutrients are explored.

STUDENT OBJECTIVES;

By the completion of this course the student will be able to;

· Describe the biochemical basis of metabolism of micro nutrients at the cellular level.

· Apply biochemical foundations in metabolism of micronutrients, to regulation of tissue metabolism, production and storage of energy and management of metabolic waste products.

· Relate physiological and biochemical function of micro nutrients to human requirements.

· Explain metabolism and function of micronutrients: vitamins, minerals and water, in relation to body health and human nutritional adaptive capabilities. 

· Evaluate nutritional investigations and report the studies published in scientific journals.

· Synthesize various cellular activities, making them meaningful at the tissue, organ and system levels.

· Apply concepts in micronutrient regulation to metabolism, energy balance and weight management.

· Describe the role and function of water and electrolytes and minerals, trace and major in the body.

· View individual life processes in relation to the whole rather than compartmentalizing these processes.

TOPICS TO BE COVERED;

I. CELLS AND THEIR NOURISHMENTS (review)

1.Cell: A Microcosm of Life; A review of physiology of the cell as a unit of life, the role of micronutrients in regulation of cellular activities will be discussed.

2.The Digestive System: Mechanism for Nourishing the Body. In this section the physiology of digestion and absorption, will be discussed as well as process involved in assimilation of absorbed micronutrients. Regulatory functions of enzymes, hormones and nervous systems are studied.

II. ENERGY PRODUCING NUTRIENTS(review)

3.The role of Vitamins and Minerals as Coenzyme in Energy Transformation, oxidative phosphorylation, formation of ATP, and energy release or consumption in chemical reactions, coupled reactions in transfer of energy, biological oxidation and electron transport chain will be studied.

III.THE REGULATORY NUTRIENTS

4. The Water Soluble Vitamins and Their Biochemical Roles.

5. Vitamins as Biochemical Indicators of Nutritional Status,

5.Fat Soluble Vitamins and Their Metabolism

6.Macro-Minerals

6. Trace Minerals

7. Ultra Trace Elements

IV.HOMEOSTATIC MAINTENANCE

9.Body Fluid and Electrolyte Balance

10.Body Composition Its Measurements, Relations to Diseases & Energy Expenditure

11.Nutrition and Biochemical Effect on Central Nervous System

12.Experimental Design and Critical Interpretation of Research 

COURSE EVALUATION

TESTS:  3 tests will be administered during the term. Total score =60%

TERM PAPER: A major term paper with at least 40 papers reviewed  =30%

CLASS PARTICIPATION: preparation and presentation of assignments =10%

TOTAL: 100%

Grading Scale :92 -100 = A 84 - 91 = B  75 - 83 = C

ATTENTION

1. Given the nature of this course, class attendance and participation are extremely important and may be taken into consideration for final grade.

2. All assignments are to be presented on time and typewritten. One point will be taken off any late assignment. 

3. This is a graduate course. Certain level of maturity is expected of the students. There are certain amount of subjectivity in evaluating the performance of the students since you are being trained for dealing with a very special population who need a great amount of compassion and care. Therefore students are expected to show responsibility and growth in this course.

SYLLABUS

1-9 Review of Cell, Energy Nutrients, Digestive and Absorptive Systems and Physiology.

1-16 REGULATORY NUTRIENTS: The Water Soluble Vitamins, Their Structures, Functions and Interactions

1-23 Study of Individual Vitamins

1-30 The Fat Soluble Vitamins, Their Structure, Functions and Interactions

Chapter Reference:

2-6 Study of Individual Vitamins

2-13 TEST # 1 

2-20 Macro Minerals, Functions, Sources, Digestion, Absorption, Transport, Interactions with other Nutrients

2-27 Study of Individual Minerals

3-6 Micro Minerals - Study of Individual Minerals

3-13  TEST #2

3-27 Body Fluids and Electrolyte Balance

4-3 Body Composition: Body Weight, Methods of Measurements

4-10 Nutrition and Central Nervous System

4-17 Nutrition Knowledge Base: Experimental Design and Critical Interpretation of Research

4-24 Developing Research proposals 

5-3 TEST #3